Testicular carcinoid tumors are very rare, accounting for less than 1% of all testicular tumors. We report a rare case of a testicular carcinoid tumor with extensive lymphatic invasion. A 42-year-old man presented with a painless, enlarged right testicular mass. There was no history of injury or discomfort in this region. Right radical orchiectomy was performed, which showed a well-defined, non-encapsulated solid white mass with calcification (7.0 × 4.5 × 3.5 cm) and absence of cystic components. Microscopic examination using hematoxylin and eosin staining of the tumor sections identified organoid, trabecular, and solid patterns with rosette formation. Extensive multifocal lymphatic invasion was observed. Immunohistochemistry was positive for synaptophysin, chromogranin, and CD56. Testicular carcinoid tumors usually show good prognoses; however, there was extensive lymphovascular invasion in this case. Thus, in the case of unusual presentation of the disease, close follow-up is necessary.
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Lymphocytic phlebitis of gastrointestinal (GI) tract is a rare diseaes. Approximately 50 cases of lymphocytic phlebitis of the GI tract have been reported. Most of these involved the colon or small intestine and presented as acute abdomen. We report the second case of lymphocytic phlebitis of the stomach. A 73-year-old female complaining of dizziness had endoscopic and computed tomography findings strongly suggested gastric cancer, while gastric biopsy was negative for carcinoma. The partial gastrectomy specimen showed lymphocytic phlebitis involving veins in the submucosa, muscularis propria, and serosa while the adjacent arteries were spared. The veins were mainly surrounded by lymphocytes. When a patient has a lesion in the GI tract that is suggesting cancer without biopsies revealing any carcinoma, the pathologist should recommend a deeper biopsy for a proper examination of the submucosa.
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A case report of gastric lymphocytic phlebitis, a rare mimic for malignancy Daniel L. Chan, Praveen Ravindran, Dorothy Chua, Jason D. Smith, King S. Wong, Michael A. Ghusn International Journal of Surgery Case Reports.2017; 41: 269. CrossRef
Sclerosing angiomatoid nodular transformation (SANT) of spleen is a rare inflammatory tumor-like vascular lesion composed of angiomatoid nodules in a fibrosclerotic background. We report herein on a case of SANT in the spleen with its pathologic features, and review the related literature. A 50-year-old woman presented with mild left upper quadrant discomfort and tenderness and she showed a 6 cm-sized solitary splenic mass on computed tomography. She underwent laparoscopic splenectomy. Grossly, the spleen showed a well circumscribed round-shaped solid mass with multinodular hemorrhagic surfaces. Microscopically, the mass consisted of multiple angiomatoid nodules surrounded by collagen bundles with fibroblasts and a lymphoplasma cell infiltration. Immunohistochemically, the cells of the angiomatoid nodules were positive for CD31, CD30, CD34, alpha-smooth muscle actin, and VWF-VIII, but they were negative for CD8, anaplastic lymphoma kinase protein, and D2-40. The patient has been under close follow-up without recurrence.
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